Suppository



Patented Jan. 29, 1924.

UNITED STATES EDWARD GEARON, OF CHICAGO, ILLINOIS.

SUPPOSITORY.

Application filed April 2 1, 1923. Serial No. 634,340.

To all'whom it may concern:

Be it known that I, EDWARD GEARON, a citizen of the United States, residing at Chicago, in the county of Cook and State of Illinois, have invented new and useful Improvements in Suppositories, of which the followingis a specification.

The wallsof the rectal or pelvic passages of the body very often become distended, inflamed, irritated, or otherwise affected, and a purpose of the present invention is to treat such parts by the use of an improved suppository,which is cylindrical, hollow, per-- forated, and has .a soluble core used to hold medicines'or drugs and also to retain in place medicinal capsules. These capsules contain a medical compound, so that whenthe suppository becomes sufliciently dissolved, while in use, and diffused, the medical compound is thoroughly distributed throughout the passage. I Another purpose of so constructing the suppository is that when it is in use in any passage of the body, the materials which hold the medicinal capsules in position are more soluble than the other substances of which the suppository is composed. These materials, which also contain medicinal sub stances. are the first to dissolve and seep through the preparations in the core anddissolve the materials which form the coating of the capsules. Thiswill release the various substances and combine them with those forming the body of the suppository, and thereby facilitate their dissolution and dif fusion in a complete medical compound throughout the surrounding parts and impregnate the insoluble absorbent materials embodied in the suppository body. The fact that the suppository body is in part insoluble is of no consequence, as the insoluble matter would be of an inert nature, and would eventually be discharged with the other or dissolved ingredients of the suppository.

A great number of drugs, because'of their imcompatible nature, can not be combined in a free state with other drugsin a suppository of proper consistency. In assembling carbolic acid and cocoa butter the former would liquefy the latter. However, any desired incompatible drugs can be used in soluble capsules imbedded in the body of this suppository, and said drugs thus applied in their natural state to the parts which are to be medicated. .It has been found that drugs used in, suppositories of the present character enclosed in capsules, are better preserved, until used, and their medicinal qualities better utilized.

Further, the impregnated materials composingthe body of the present suppository include absorbent insoluble substances to absorb the medicinal ingredients of the capsules and adapted to keep them longer in contact with the parts to be medicated. Furthermore, the present suppository is of hollow construction which allows the natural flow of air, gases or liquids through thepassages in which they are used.

Moreover, since the present suppository is made substantially entirely of solvent ma-. terials it can be made very flexible, if desired, by immersing it in water or oil. This also decreases the pain, when inserting it in the passages in which it is used, without any loss of the drugs enclosed in the capsules.

Also, with proper manufacturing facilities the present suppository can be made very economically and marketed at a reasonable price.

A still further purpose is the provision of meansfor inserting the suppository without rupturing the same and soilingthe hands. It is to be understood that the particulars herein given are in no way limitative and that while still keeping within the scope of the invention, any desired modifications of detail and desired proportions may be made in the construction according to circumstances.

The invention comprises further features and combinations of parts, to be further set forth, illustrated in. the drawings, and claimed,-

In the drawings:-

Figure 1 is a longitudinal sectional view of the improved suppository constructed in accordance with the invention;

Fig. 2 is a transverse sectional view on line 22 ofone end of the suppositoryin Fig. 1; y

Fig. 3 is also a transverse sectional view through the opposite end thereof on line 33 of Fig. 1.

Referring to the drawings, 1 designates a core comprising a tube, preferably of gelatine, or other soluble material. The interior rows of standard capsules 4 are applied on '4 the exterior adjacent the other end of "the core. The assembly is then placed in a mold, and formed with an external jacket 5, which is constructed of partially soluble gelatine or similar material. This jacket givesthe aligned openings 7 and 8 for the reception fill suppository the proper form for handling and inserting thesame, and'at the same time protecting the medicated vessels within. It

is to be noted that the jacket closes in -'-upon the top capsules as at 6 so as to firmly hold the latter to the tube in case the .adhesive element gives way in a dry room or loses its adhesive qualities due to vibration. "In order to apply the device the opposite ends of the jacket are provided with axially of a rod or stem 9, which constitutes means for insertin the suppository in the passage to be treatec One end of the rod or stem is provided with a stop or flange 10, which, when inserting the suppository, acts as an abutment for forcing the suppository into the passage. This flange also limits the insertion of the rod or stem into the suppository. The rod or stem isalso supplied with a handle 11 beyond the flange. The tool or instrument for inserting the suppository is constructed of relatively stiff (not hard) rubber, in order that it may conform to some extent to the contour of the passage which receives the suppository. Obviously, the instrument or tool is-withdrawn after the suppository has been fully inserted. The constructionin Fig. lis enlarged about three or four times the actual size. The core 1 has a plurality of perforations 12 in its wall to facilitate the passage of themedicinal substances, as the capsules and the other soluble parts of the suppository aredissolving and diffusing.

It is obvious that pellets, tablets or cubes of medicinal materials may be used in the construction of the present suppositories in the same manner and for the same purposes as the medicinal capsules and it is to be understood that this construction includes their use. 7

The larger or cupped portions of the capsules 2 and fl may be molded with the core 1 if desired and the other medicament hold.- ing sections inserted thereinto. This will save the time otherwise spent in. sticking the capsules to the core after they havebeen filled.

Having set forth the invention, what is claimed is:

1. A medicinal suppository "including a hollow perforated core, a series of soluble medicinal capsules, and an exterior partially soluble absorbent-medicinal body, in which said core and capsules are imbedded.

'2. A medicinal suppository including a hollow perforated core, a series of soluble medicinal capsules, and an exterior partially soluble absorbent medicinal body, in which said core and capsules are imbedded,said suppository having a central passage for the reception of aninstrument, whereby the suppository may be inserted in a passage to be treated.

3. A medicinal suppository including a soluble hollow core, a plurality of soluble medicinal capsules arranged interiorly and exteriorly at the endsthereof, and an absorbent medicinal partially soluble body enclosing the core and capsules, said capsules having medicinal properties, which combine with the. medicinal ingredients of the body, when the latter are partially dissolved.

4. A medicinal suppository including a hollow soluble core and a series of soluble medicine-enclosing capsules, and anabsorbent medicinal. hollow body. encasing said core andcapsules. I

5. A medicinal suppository including a hollow soluble core and a series ofsoluble medicine-enclosing capsules, and an absorbent medicinal hollow body encasing said core and capsules, said body having an open passa e therethrough from end to end.

6. partially solvent medicinal suppository comprising a body, a hollow soluble core imbedded therein, a plurality of series of medicine-enclosing capsules, one series being assembled exteriorly of the core at one end thereof, the other series interiorly of the core at the opposite end, said core having a plurality of perforations ,to permit the heat and ,moisture in the passage to be treated to facilitate dissolution and diffusion of the internal and external capsules with the medicinal properties of the body, said body having a passage therethrouglrfrom' end to end for the reception of an instrument, whereby the suppository may be inserted.

7. A medicinal suppository including a hollow perforated core, a series, of soluble medicinal capsules, halves of said capsules being ,adhesively secured to said core, and an exterior partially soluble absorbent medicinal body in which said core and capsules are embedded.

In testimony whereof I afiix my signature.

' EDWARDGEARON. 

